The verse is a hymn of praise to Lord Vishnu. Here's the meaning: Shantakaram - He who is peaceful and calm, Bhujagashayanam - Who reclines on the serpent (Shesha), Padmanabham - Who has a lotus navel, Suresham - The lord of all gods, Vishvadharam - The support of the universe, Gaganasadrisham - Who is boundless and omnipresent like the sky, Meghavarnam - Whose complexion is like that of a dark cloud, Shubhangam - Who is auspicious and beautiful, Lakshmikantam - The consort of Goddess Lakshmi, Kamalanayanam - Who has lotus-like eyes, Yogibhirdhyanagamyam - Who is attainable through meditation by yogis, Vande Vishnum - I bow to Vishnu, Bhavabhayaharam - Who removes the fear of worldly existence, Sarvalokaikanatham - The lord of all the worlds. Overall, this hymn glorifies Lord Vishnu, depicting his serene and divine nature, his cosmic form, and his role as the protector and sustainer of the universe. It is a prayer seeking refuge in Vishnu and expressing deep devotion and reverence.